THE EFFECT OF AROMATASES INHIBITOR-BASED PRODUCTS ON COW REPRODUCTIVE ABILITY

Mycotoxin zearalenone is a phytoestrogenic substance that can disrupt the functioning of organs reproductive system cows. At same time, hyperestrogenic state occurs, which
 leads to overeating, multiple unsuccessful inseminations and infertility cows.
 The purpose research investigate effect single application drugs based on aromatase inhibitors main biochemical hormonal parameters blood cows, as well establish their effectiveness during spontaneous expression desire when applying synchronization schemes.
 dose dynamics sex hormones in which directly affect formation dominant follicle its ovulation, was investigated. 1.56-fold decrease estradiol, 1.67-fold increase progesterone, 1.29-fold luteinizing hormone, 1.76-fold follicle-stimulating hormone were found. maturation ovulation at size 22 24 mm have been established. A change serum cows after use products an inhibitor revealed. tendency established restore level calcium 2.01±0.27 mmol/l, phosphorus – 1.1±0.41 magnesium 0.87±0.11 selenium –1.0± 0.1 mmol/l. creatinine decreased by 1.2 times compared sick animals, indicators liver transferases also tended decrease. significant urea index 1.69 established, indicates restoration protein lipid metabolism.
 fertilization with manifestation sexual using agents studied. fertility rate ranged from 69.39% older than 5 years 80.39% 1st calving.
 positive inhibitors, introduced before estrus schemes development follicle, luteogenesis appearance new wave development. Fertilization averaged 68.1% 76.42%.